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Mouse anti-human Integrin beta 3 (CD61) antibody - Clone PM6/13
Reagent NameHuman Integrin beta 3 antibodyImmunogenHuman platelet membranesRelevanceIntegrin beta 3 is also known as glycoprotein IIIa and in a complex with the integrin alpha 2b subunit forms the receptor for fibrinogen, fibronectin and von Willebrand Factor on activated platelets. Integrin beta 3 can also complex with alpha V integrin. The antibody...
Published: 12/12/2023
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Inventor(s):
Kalwant Authi
,
John Michael Wilkinson
Keywords(s):
Category(s):
Research Tools - Cell adhesion proteins
Mouse anti-human Vinculin antibody - Clone V284
Reagent NameMouse anti-human Vinculin antibodyImmunogenPurified human platelet vinculinRelevanceVinculin is a 117 kDa membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton.Cross reactivityHuman, rabbit, rat, chicken, mouse.SpecificityEpitope not mapped. Recognises...
Published: 12/12/2023
|
Inventor(s):
Kalwant Authi
,
John Michael Wilkinson
Keywords(s):
Category(s):
Research Tools - Cell adhesion proteins
Mouse anti-human integrin alpha 2b (CD41) antibody - Clone PM6/248
Reagent NameMouse anti-human integrin alpha 2b (CD41) antibodyImmunogenHuman platelet membranesRelevanceIntegrin alpha 2b is also known as glycoprotein IIb and in a complex with the integrin beta 3 subunit forms the receptor for fibrinogen, fibronectin and von Willebrand Factor on activated platelets. The antibody activates platelets under stirring...
Published: 14/05/2024
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Inventor(s):
Kalwant Authi
,
John Michael Wilkinson
Keywords(s):
Category(s):
Research Tools - Cell adhesion proteins
Mouse anti-human Talin antibody - Clone TA205
Reagent NameMouse anti-human Talin antibodyImmunogenHuman platelet talin.RelevanceTalin is a cytoskeletal protein that is found concentrated in focal adhesions. It is capable of linking integrins to the actin cytoskeleton either directly or indirectly by interacting with vinculin and alpha-actininCross reactivityTA205 immunoblots a 225 kDa protein in...
Published: 14/05/2024
|
Inventor(s):
Kalwant Authi
,
John Michael Wilkinson
Keywords(s):
Category(s):
Research Tools - Cell adhesion proteins